When we went to TDR, we actually went to TDL first and TDS second. That's because we had 4 full days in the parks and we wanted our last day to be spent at TDS, soaking in its awesomeness. We were alternating parks, we did TDL-TDS-break day to go to the Ghibli Museum-TDL-TDS.
I'm not saying that would work for everyone, but it worked well for us. We threw a break day in there because our feet and backs were so sore after being at the parks from an hour before opening until closing time. But, a lot of other people like to do it straight through and use the park hopper option towards the end.