I'm a big American flyer (have 150,000+ miles with them, credit card holder, etc...), and I've been wholeheartedly disappointed with how they've handled the pandemic. While I've been on almost empty American flights over the past several months, most have been packed by even pre-COVID standards. A total free-for-all when disembarking. Not a lot of mask enforcement either. I really don't care what they say about the air circulation, air particles, etc..., you're not going to convince me that that is totally safe.
And yes, I'd prefer the middle seat open. Will it keep me from flying? No; I really don't have much of a choice these days with work, family needs, etc... and I accept the risks. Anyone flying should go in expecting the risk these days.